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P3-277 The role of molecular chaperones in the metabolism of tau

โœ Scribed by Taylor, Julie P.; Petrucelli, Leonard; Kehoe, Kathryn; Hutton, Michael


Book ID
122468701
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
167 KB
Volume
25
Category
Article
ISSN
0197-4580

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Molecular chaperone-mediated tau protein
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## Abstract Intracellular accumulation of filamentous tau proteins is a defining feature of neurodegenerative diseases termed __tauopathies__. The pathogenesis of tauopathies remains largely unknown. Molecular chaperones such as heat shock proteins (HSPs), however, have been implicated in tauopathi