The early effects of partial outflow obstruction on contractile properties of diabetic and non-diabetic rat bladder
✍ Scribed by Öztürk, Bülent ;Çetinkaya, Mesut ;Gür, Serap ;Ugurlu, Özgür ;Öztekin, Volkan ;Aki, Fazil
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 283 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0300-5623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The effects of chronic partial outflow obstruction in rats were investigated. The urethra of male rats was partially obstructed for 3 or 6 months and bladder function was compared with that of age-matched controls. Bladder function was studied in vivo by infusion cystometry and in vitro by measuring
Partial outlet obstruction induces significant alteration in detrusor contractility. A mild obstruction can result in increased contractile force, whereas severe obstruction results in marked contractile dysfunction. The cellular mechanisms mediating these alterations in the contractile response are
Bladder outlet obstruction induces a rapid hypertrophy characterized by increased bladder mass and collagen deposition. An increase in collagen is likely to reduce the contractility and compliance of bladder wall. This study was undertaken to investigate the effects of partial bladder outlet obstruc