## Abstract The viral factor E7 plays a key role in the wellβestablished association between βhighβriskβ Human Papillomavirus (HPV) infection and the development of epithelial malignant tumors, as uterine cervix and anoβgenital cancer. To delve into the molecular mechanisms of HPVβmediated cell tra
The E7 Oncoprotein of Human Papillomavirus Type 16 Interacts with F-Actin in Vitro and in Vivo
β Scribed by Osvaldo Rey; Sora Lee; Marcel A. Baluda; Jerry Swee; Bradley Ackerson; Robert Chiu; No-Hee Park
- Book ID
- 112272456
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 416 KB
- Volume
- 268
- Category
- Article
- ISSN
- 0042-6822
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Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel
## Abstract The carcinogenesis of human papillomaviruses type 16 (HPVβ16) is mainly due to its two oncoproteins, E6 and E7. Their carcinogenic features in term of their relationship with Bclβ2 family are still unclear. We thus aimed to analyze the expression of Bclβ2 family members, Bclβ2, Bax, and
Human papillomaviruses (HPVs) have been recognized as an essential pathogenic factor in anogenital cancer. HPV DNA has also been found in a subgroup of head-and-neck squamous-cell carcinomas (HNSCCs), and a causative role of the virus in the development of these tumors has been suggested by the conc