✦ LIBER ✦

The E5 protein of BPV-4 interacts with the heavy chain of MHC class I and irreversibly retains the MHC complex in the Golgi apparatus

✍ Scribed by Marchetti, B; Ashrafi, G H; Dornan, E S; Araibi, E H; Ellis, S A; Campo, M S

Book ID: 110070276
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 223 KB
Volume: 25
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1209245

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The bovine papillomavirus oncoprotein E5

The bovine papillomavirus oncoprotein E5 retains MHC class I molecules in the Golgi apparatus and prevents their transport to the cell surface

✍ Marchetti, Barbara; Ashrafi, G Hossein; Tsirimonaki, Emmanouella; O'Brien, Phili 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 619 KB

E5 protein of human papillomavirus 16 do

E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domain

✍ G. Hossein Ashrafi; Mohammad Haghshenas; Barbara Marchetti; M. Saveria Campo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 543 KB

## Abstract Human papillomavirus type 16 E5 protein (HPV‐16 E5) is expressed early in papillomavirus infection and is localised primarily in the cell Golgi apparatus (GA) and endoplasmic reticulum. E5 prevents transport of the major histocompatibility class I (MHC I; HLA class I in humans) to the c

Auto-tumor immunity in patients with sol

Auto-tumor immunity in patients with solid tumors: participation of CD3 complex and MHC class I antigens in the lytic interaction

✍ Farkas Vánky; Trudie Roberts; Eva Klein; Jan Willems 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 446 KB

Transcriptional regulation of the major

Transcriptional regulation of the major histocompatibility complex (MHC) class I heavy chain, TAP1 and LMP2 genes by the human papillomavirus (HPV) type 6b, 16 and 18 E7 oncoproteins

✍ Georgopoulos, Nikolaos T; Proffitt, Joanne L; Blair, G Eric 📂 Article 📅 2000 🏛 Nature Publishing Group 🌐 English ⚖ 181 KB

All 4 di-leucine motifs in the first hyd

All 4 di-leucine motifs in the first hydrophobic domain of the E5 oncoprotein of human papillomavirus type 16 are essential for surface MHC class I downregulation activity and E5 endomembrane localization

✍ Marc S. Cortese; G. Hossein Ashrafi; M. Saveria Campo 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 342 KB 👁 1 views

## Abstract The E5 oncoprotein of human papillomavirus type 16 downregulates surface MHC Class I and interacts with the heavy chain of the MHC complex __via__ the first hydrophobic domain, believed to form the first helical transmembrane region (TM1) of E5. TM1 contains 4 equally spaced di‐leucine