The E2F family: specific functions and overlapping interests
โ Scribed by Attwooll, Claire; Denchi, Eros Lazzerini; Helin, Kristian
- Book ID
- 110030878
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 282 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0261-4189
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The E2F family of transcription factors plays a key role in the control of cell-cycle progression. Some family members may act as oncogenes, others as tumor-suppressor genes. The genetic changes and the expression of E2F-1 and -3 were examined in human gastric and colorectal carcinomas by Southern,