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The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle

✍ Scribed by Ray, Peter N.; Worton, Ronald G.; Zubrzycka-Gaarn, Elizabeth E.; Bulman, Dennis E.; Karpati, George; Burghes, Arthur H. M.; Belfall, Bonnie; Klamut, Henry J.; Talbot, Jim; Hodges, Robert S.


Book ID
109754414
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
603 KB
Volume
333
Category
Article
ISSN
0028-0836

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Facioscapulohumeral muscular dystrophy (FSHD) is a relatively common autosomal dominant neuromuscular disorder. The gene for FSHD has recently been assigned to chromosome 4q35. Although abnormal mitochondrial and biochemical changes have been observed in FSHD, the molecular defect is unknown. In add