Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy
β Scribed by Adriana Pertille; Candida Luiza Tonizza De Carvalho; Cintia Yuri Matsumura; Humberto Santo Neto; Maria Julia Marques
- Book ID
- 108785918
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 309 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0959-9673
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## Abstract In the muscular dystrophic (mdx) mouse, which is characterized by deficient dystrophin expression and provides a model of Duchenne's muscular dystrophy, we previously demonstrated marked central nervous system alterations and in particular a quantitative reduction of corticospinal and r
## Abstract Although the genetic and biochemical bases of many of the muscular dystrophies have been elucidated, the pathophysiological mechanisms leading to muscle cell death and degeneration remain elusive. Among the most well studied of the dystrophies are those due to defects in proteins that m