✦ LIBER ✦

The drug methoxsalen, a suicide substrate for cytochrome P-450, decreases the metabolic activation, and prevents the hepatotoxicity, of carbon tetrachloride in mice

✍ Scribed by Gilles Labbe; Veronique Descatoire; Philippe Letteron; Claude Degott; Marina Tinel; Dominique Larrey; Yasna Carrion-Pavlov; Jean Geneve; Gilles Amouyal; Dominique Pessayre

Book ID: 115779555
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 928 KB
Volume: 36
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(87)90183-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Methoxsalen decreases the metabolic acti

Methoxsalen decreases the metabolic activation and prevents the hepatotoxicity and nephrotoxicity of chloroform in mice

✍ Philippe Lettéron; Claude Degott; Gilles Labbe; Dominique Larrey; Veronique Desc 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 649 KB

The prevention of carbon tetrachloride-i

The prevention of carbon tetrachloride-induced hepatotoxicity in mice by α-hederin: Inhibiton of cytochrome P450 2E1 expression

✍ Hye Gwang Jeong; Hyeon Yong Park 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 528 KB

Improvac does not modify the expression

Improvac does not modify the expression and activities of the major drug metabolizing enzymes cytochrome P450 3A and 2C in pigs

✍ Jana Tomankova; Martin Krøyer Rasmussen; Kristina Andersson; Bo Ekstrand; Galia 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 222 KB

Drug metabolism in the novikoff hepatoma

Drug metabolism in the novikoff hepatoma. Evidence for a mixed function oxidase system and partial purification of cytochrome P-450 reductase

✍ Susan E. Saine; Wan-Fen Fang; Henry W. Strobel 📂 Article 📅 1978 🏛 Elsevier Science ⚖ 837 KB

In-vivo and In-vitro Metabolic Clearance

In-vivo and In-vitro Metabolic Clearance of Midazolam, a Cytochrome P450 3A Substrate, by the Liver under Normal and Increased Enzyme Activity in Rats

✍ FUMIKO HIGASHIKAWA; TERUO MURAKAMI; TATSUYA KANEDA; MIKIHISA TAKANO 📂 Article 📅 1999 🏛 Pharmaceutical Press 🌐 English ⚖ 97 KB

Mechanism for the protective effects of

Mechanism for the protective effects of silymarin against carbon tetrachloride-induced lipid peroxidation and hepatotoxicity in mice: Evidence that silymarin acts both as an inhibitor of metabolic activation and as a chain-breaking antioxidant

✍ Philippe Lettéron; Gilles Labbe; Claude Degott; Alain Berson; Bernard Fromenty; 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 907 KB