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The drug methoxsalen (8-methoxypsoralen) is a potent inhibitor of cytochrome P-450 in rats and in humans


Book ID
123057518
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
77 KB
Volume
1
Category
Article
ISSN
0168-8278

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Key words: bisphosphonate; P-450 inhibitor, pharmacokinetics; cardiopulmonary; conscious rat U-91502, a bisphosphonate for arthritic inflammation treatment, was evaluated for its parental toxicity. The objective was to differentiate between the parent drug and a reactive metabolite(s) as the proxima