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The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukaemias

✍ Scribed by Inga Worner; Estela Matutes; Peter C. L. Beverley; Daniel Catovsky


Book ID
114712123
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
585 KB
Volume
74
Category
Article
ISSN
0007-1048

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CD4, CD8 and the role of CD45 in T-cell
✍ Jeffrey A. Ledbetter; Julie P. Deans; Alejandro Aruffo; Laura S. Grosmaire; Stev πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 1009 KB

CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta