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Distribution of the CD45R antigen in the maturation of lymphoid and myeloid series: the CD45R negative phenotype is a constant finding in T CD4 positive lymphoproliferative disorders

✍ Scribed by C. Huelin; M. Gonzalez; S. Pedrinaci; B. de la Higuera; M. A. Piris; J. San Miguel; F. Ruiz-Cabello; F. Garrido

Book ID: 114711575
Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 662 KB
Volume: 69
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.1988.tb07619.x

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Cover Picture: The cover image features

Cover Picture: The cover image features a frozen section from an embryonic day 16 mouse spleen stained by immunofluorescence to demonstrate the presence and location of lymphoid tissue inducer (LTi) cells. Withers et al. (pp. 3240–3245) show that these cells form the focus of lymphocyte accumulation in the developing mouse spleen. Red staining for CD45 marks haemopoietic cells, green shows IL-7Rα expression, and CD4 expression is in blue. LTi cells that express all markers (in white) cluster around blood vessels in the embryonic spleen where signalling to stromal cells initiates lymphocyte recruitment. – Eur. J. Immunol. 11/2007

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