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The dissolution property of raloxifene HCl solid dispersion using hydroxypropyl methylcellulose

โœ Scribed by Myeong Jun Oh, Jung Bo Shim, Hanna Yoo, Ga Young Lee, Hansu Jo, Su Mi Jeong, Soon Hong Yuk, Dongwon Lee, Gilson Khang


Book ID
118302522
Publisher
The Polymer Society of Korea
Year
2012
Tongue
English
Weight
732 KB
Volume
20
Category
Article
ISSN
1598-5032

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The aim of this study was to investigate the solubility of mefenamic acid (MA), a highly cohesive, poorly water-soluble drug in a copolymer of polyoxyethylenepolyoxypropylene (Lutrol F68 1 ), and to understand the effect drug polymer solubility has on in vitro dissolution of MA. Solid dispersions (S