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The dissolution of nortriptyline HCl from polyethylene glycol solid dispersions

โœ Scribed by D.Q.M. Craig; J.M. Newton


Book ID
113365961
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
569 KB
Volume
78
Category
Article
ISSN
0378-5173

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The dissolution characteristics of dicumarol were markedly enhanced by preparing dispersions of drug in polyethylene glycol 4000. Solid dispersions of varying weight fractions were formed by a melt method without measurable drug degradation or evaporation. There were no significant differences in di