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The Disposition of Morphine and Morphine-3-glucuronide in the Isolated Perfused Rat Liver: Effects of Altered Perfusate Flow Rate

โœ Scribed by JOSEPHINE A. O'BRIEN; ROGER L. NATION; ALLAN M. EVANS


Book ID
118110268
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
668 KB
Volume
48
Category
Article
ISSN
2042-7158

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Primaquine disposition in the isolated p
โœ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in