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Mefloquine Effect on Disposition of Halofantrine in the Isolated Perfused Rat Liver

โœ Scribed by Kathleen U. Leo; David L. Wesche; Mark T. Marino; Thomas G. Brewer

Book ID
118110138
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
610 KB
Volume
48
Category
Article
ISSN
2042-7158

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Primaquine disposition in the isolated p
Primaquine disposition in the isolated perfused rat liver: Effect of mefloquine induced bile flow reduction
โœ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in