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Disposition of the antimalarial, mefloquine, in the isolated perfused rat liver

โœ Scribed by Michael D. Coleman; Lawrence Fleckenstein; Lisa A. Shipley; Melvin H. Heiffer

Book ID
115780691
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
598 KB
Volume
37
Category
Article
ISSN
0006-2952

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๐Ÿ“œ SIMILAR VOLUMES

Primaquine disposition in the isolated p
Primaquine disposition in the isolated perfused rat liver: Effect of mefloquine induced bile flow reduction
โœ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in