The disposition of inhaled lysine theophylline in volunteers
β Scribed by S. H. D. Jackson; J. K. Wiffen; A. Johnston; C. A. Peverel-Cooper
- Book ID
- 104798999
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 250 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0031-6970
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π SIMILAR VOLUMES
The effect of domperidone (2 mg kg-') on the pharmacokinetics of a single oral dose of theophylline (25 mg kg-') was studied in the rat. Theophylline concentrations were measured serially for 12 h using an HPLC technique. Domperidone did not have any significant effect on any of the four parameters
## Abstract Theophyllineβ7βacetic acid (T7AA) was administered intravenously to rabbits so that its distribution and rate of elimination could be ascertained. The analytical techniques used were liquid scintillation counting (^14^C) and high pressure liquid chromatography. T7AA was eliminated rapid