✦ LIBER ✦

Disposition of intravenous theophylline-7-acetic acid in rabbits

✍ Scribed by J. A. Owen; K. Nakatsu

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 430 KB
Volume: 1
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bdd.2510010405

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Theophylline‐7‐acetic acid (T7AA) was administered intravenously to rabbits so that its distribution and rate of elimination could be ascertained. The analytical techniques used were liquid scintillation counting (^14^C) and high pressure liquid chromatography. T7AA was eliminated rapidly in the urine; the T~½~ was 11·6 min. This drug appears to accumulate in the kidney because after 60 min, approximately 15 per cent of the intravenous dose was found in that organ.

📜 SIMILAR VOLUMES

The assay and absorption kinetics of ora

The assay and absorption kinetics of oral theophylline−7-acetic acid in the human

✍ S. Sved; I. J. McGilveray; N. Beaudoin 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB 👁 1 views

## Abstract A sensitive and specific method for the estimation of theophylline−7‐acetic acid in plasma by high performance liquid chromatography is described. Acidified plasma is extracted with chloroform‐__n__‐butanol (85: 15), back extracted with phosphate buffer (0.5 moll^−1^, pH 6.5), and final

ChemInform Abstract: Ammonium Nitrate in

ChemInform Abstract: Ammonium Nitrate in Acetic Acid, an Efficient Reagent for the Nitration of Perimidines and the One-Pot Synthesis of 6(7)-Aminoperimidines.

✍ A. V. Aksenov; A. S. Lyakhovnenko; T. S. Perlova; I. V. Aksenova 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 23 KB

ChemInform Abstract: Efficient Condensat

ChemInform Abstract: Efficient Condensation of p-Substituted Phenols, p-Thiocresol and 2,7-Dihydroxynaphthalene with Malonaldehyde Tetramethyl Acetal in Trifluoroacetic Acid.

✍ Ahmad Banihashemi; Ali Rahmatpour 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views