The Discovery of Tadalafil: A Novel and Highly Selective PDE5 Inhibitor. 1: 5,6,11,11a-Tetrahydro-1 H -imidazo[1‘,5‘:1,6]pyrido[3,4- b ]indole-1,3(2 H )-dione Analogues
✍ Scribed by Daugan, Alain; Grondin, Pascal; Ruault, Cécile; Le Monnier de Gouville, Anne-Charlotte; Coste, Hervé; Kirilovsky, Jorge; Hyafil, François; Labaudinière, Richard
- Book ID
- 120504406
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 131 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-2623
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📜 SIMILAR VOLUMES
The geminal coupling constant C-8.0 Hz) for the N-CH2-0 protons in hexahydro-l&3!-pyrido [1,2-cl[1,3loxazine (1)' when compared with the corresponding n.m.r. parameter in cis-8,12a, -
The title compound, C~22~H~25~N~3~O~3~, also known as fumitremorgine C, was isolated from the ethyl acetate extract of Penicillium __sp__. To a first approximation, the molecule is flat with the exception of the –C(H)=CMe~2~ side arm, which is perpendicular to the remaining atoms. Molecules associat