✦ LIBER ✦

The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia

✍ Scribed by Ginny D. Ho; Shu-Wei Yang; Jennifer Smotryski; Ana Bercovici; Terry Nechuta; Elizabeth M. Smith; William McElroy; Zheng Tan; Deen Tulshian; Brian McKittrick; William J. Greenlee; Alan Hruza; Li Xiao; Diane Rindgen; Deborra Mullins; Mario Guzzi; Xiaoping Zhang; Carina Bleickardt; Robert Hodgson

Book ID: 113496455
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 932 KB
Volume: 22
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2011.11.127

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of orally active pyrazoloquino

Discovery of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia

✍ Shu-Wei Yang; Jennifer Smotryski; William T. McElroy; Zheng Tan; Ginny Ho; Deen 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 977 KB

Discovery of a Potent, Selective, and Or

Discovery of a Potent, Selective, and Orally Active Proteasome Inhibitor for the Treatment of Cancer

✍ Dorsey, Bruce D.; Iqbal, Mohamed; Chatterjee, Sankar; Menta, Ernesto; Bernardini 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 161 KB

Discovery of benzoylisoindolines as a no

Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors

✍ Emmanuel Pinard; Daniela Alberati; Markus Bender; Edilio Borroni; Virginie Brom; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 730 KB

Substituted Pyrazolopyridopyridazines as

Substituted Pyrazolopyridopyridazines as Orally Bioavailable Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile Dysfunction

✍ Yu, Guixue; Mason, Helen; Wu, Ximao; Wang, Jian; Chong, Saeho; Beyer, Bruce; Hen 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 60 KB

Discovery of potent, selective, and meta

Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors

✍ Essa Hu; Roxanne K. Kunz; Shannon Rumfelt; Ning Chen; Roland Bürli; Chun Li; Kri 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 776 KB

Optimization of Purine Based PDE1/PDE5 I

Optimization of Purine Based PDE1/PDE5 Inhibitors to a Potent and Selective PDE5 Inhibitor for the Treatment of Male ED.

✍ Craig D. Boyle; et al. et al. 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 19 KB 👁 1 views

## Abstract For Abstract see ChemInform Abstract in Full Text.