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The Discovery of Potent Antitumor Agent C11-Deoxypsymberin/irciniastatin A: Total Synthesis and Biology of Advanced Psymberin Analogs

✍ Scribed by Huang, Xianhai; Shao, Ning; Huryk, Robert; Palani, Anandan; Aslanian, Robert; Seidel-Dugan, Cynthia


Book ID
126046964
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
137 KB
Volume
11
Category
Article
ISSN
1523-7060

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ChemInform Abstract: Total Synthesis of
✍ A. FUERSTNER; H. WEINTRITT πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 2 views

Total Synthesis of the Potent Antitumor Agent Roseophilin: A Concise Approach to the Macrotricyclic Core. -The first synthesis of the intricate macrotricyclic core segment (XIV) of the title antibiotic is presented. The approach merges the potential of an established Pd-catalyzed macrocyclization r