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The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3 H ]indol]-2′(1′ H )-ones as Orally Bioavailable Antitumor Agents

✍ Scribed by Sampson, Peter B.; Liu, Yong; Patel, Narendra Kumar; Feher, Miklos; Forrest, Bryan; Li, Sze-Wan; Edwards, Louise; Laufer, Radoslaw; Lang, Yunhui; Ban, Fuqiang; Awrey, Donald E.; Mao, Guodong; Plotnikova, Olga; Leung, Genie; Hodgson, Richard; Mason, Jacqueline; Wei, Xin; Kiarash, Reza; Green, Erin; Qiu, Wei; Chirgadze, Nickolay Y.; Mak, Tak W.; Pan, Guohua; Pauls, Henry W.

Book ID: 125425058
Publisher: American Chemical Society
Year: 2014
Tongue: English
Weight: 869 KB
Volume: 58
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm500537u

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