The discovery of potent and selective do
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W Stephen Faraci; Stevin H Zorn; Mark A Sanner; Anton Fliri
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Article
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1998
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Elsevier Science
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English
β 663 KB
The identification of a novel dopamine receptor subtype, referred to as the D4 receptor, which binds the atypical antipsychotic drug clozapine with high potency, has led to the initiation of a drug discovery program that aims to find novel inhibitors of this receptor subtype. A selective screening s