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The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: Half a century of anxiolytic drugs

✍ Scribed by Francisco López-Muñoz; Cecilio Álamo; Pilar García-García

Book ID
116610778
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
879 KB
Volume
25
Category
Article
ISSN
0887-6185

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Beyond the benzodiazepines: The search for new anxiolytics. A summary of pre-clinical approaches
✍ Sandra E. File 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 798 KB

The clinical efficacy of the benzodiazepines in reducing anxiety is widely accepted. However, the search for novel anxiolytics continues, motivated by the hope of finding a non-sedative anxiolytic. This article reviews the pre-clinical evidence for new compounds as it relates both to their anxiolyti