Photosensitized oxygenation of a-keto carboxylic acids in the presence of diazo compounds afforded the corresponding carboxylic acids and carbon dioxide in high yields; oxidative decarboxylation by carbonyl oxides occurred. Hydroxylations catalyzed by several dioxygenases require cc-keto carboxylic
The direct photo-oxidative decarboxylation of α-oxo-carboxylic acids
✍ Scribed by R. Stephen Davidson; Dean Goodwin; Geoffrey Turnock
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 225 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
a-Oxo-carboxylic acids undergo photo-oxidative decarboxylation from both C-l and C-2 positions, and reaction does not involve singlet oxygen: a mechanism involving an electron transfer reaction is postulated.
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