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The Dimerization Mechanism of LIS1 and its Implication for Proteins Containing the LisH Motif

✍ Scribed by Agnieszka Mateja; Tomasz Cierpicki; Marcin Paduch; Zygmunt S. Derewenda; Jacek Otlewski


Book ID
116662787
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
499 KB
Volume
357
Category
Article
ISSN
0022-2836

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## Abstract Size exclusion chromatographic analyses showed that Ca^2+^‐free VILIP‐1 contained both monomeric and dimeric forms, while no appreciable dimerization was noted with Ca^2+^‐free VILIP‐3. Swapping of EF‐hands 3 and 4 of VILIP‐1 with those of VILIP‐3 caused the inability of the resulting c