The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide
✍ Scribed by Gerard A. Schellekens; Hendrik Visser; Ben A. W. De Jong; Frank H. J. Van Den Hoogen; Johanna M. W. Hazes; Ferdinand C. Breedveld; Walther J. Van Venrooij
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 482 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Recent data have shown that the most prominent and longest known genetic risk factors for rheumatoid arthritis (RA), HLA–DRB1 shared epitope alleles, are only associated with RA that is characterized by the presence of antibodies against cyclic citrullinated peptide (anti‐
## Abstract ## Objective The evolution of the rheumatoid arthritis (RA)–specific anti–cyclic citrullinated peptide (anti‐CCP) antibody response, as measured by the isotypes of anti‐CCP, has not been described. This study was undertaken to determine anti‐CCP isotype usage in patients with undiffere