Anti–cyclic citrullinated peptide antibody in early rheumatoid arthritis: Comment on the editorial by Scott
✍ Scribed by Walther J. van Venrooij; Leo B. A. van de Putte; Frank H. J. van den Hoogen
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 32 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Anti–cyclic citrullinated peptide (anti‐CCP) antibodies are rheumatoid arthritis (RA)–specific serologic markers. RA susceptibility has been associated with HLA–DRB1 shared epitope (SE) alleles and single‐nucleotide polymorphism (SNP) haplotypes in the peptidyl arginine de
## Abstract ## Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic citrullinated peptide (anti‐CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). ## Methods We studied 1,723 Caucasian RA patients enrolled in the