The Diagnostic, Prognostic, and Predictive Potential of MicroRNA Biomarkers in Colorectal Cancer
β Scribed by Yuji Toiyama; Ajay Goel
- Book ID
- 107535819
- Publisher
- Current Science Inc.
- Year
- 2012
- Tongue
- English
- Weight
- 197 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1556-3790
No coin nor oath required. For personal study only.
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Colorectal cancer is a significant cause of morbidity and mortality in industrialized societies and the second most frequent cause of cancer death in the United States. Surrogate endpoint biomarkers are gaining wide acceptance in early diagnosis and short-term cancer chemoprevention trials in place
Colorectal cancer is the third most common cancer with a 5-year survival rate of 30-65%. A portion of the interpatient variability in its clinical outcome is attributed to inherited and somatic genetic factors. Although numerous research articles have investigated these factors in colorectal cancer,