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The diacylglycerol kinase inhibitor R 59022 potentiates bombesin stimulation of protein kinase C activity and DNA synthesis in swiss 3T3 cells

✍ Scribed by Clive Morris; Peter Rice; Enrique Rozengurt

Book ID
117058090
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
348 KB
Volume
155
Category
Article
ISSN
0006-291X

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Protein kinase D2 potentiates MEK/ERK/RS
Protein kinase D2 potentiates MEK/ERK/RSK signaling, c-Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells
✍ James Sinnett-Smith; Elena Zhukova; Osvaldo Rey; Enrique Rozengurt πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 315 KB

## Abstract Protein kinase D (PKD) plays an important role in mediating cellular DNA synthesis in response to G protein‐coupled receptor (GPCR) agonists but the function of other isoforms of the PKD family has been much less explored. Here, we examined whether PKD2 overexpression in Swiss 3T3 cells