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The developmental expression and activity of peptidylarginine deiminase in the mouse

✍ Scribed by L.B Pritzker; T.A Nguyen; M.A Moscarello

Book ID
117477663
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
87 KB
Volume
266
Category
Article
ISSN
0304-3940

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## Abstract Peptidylarginine deiminases (PADs) are a group of posttranslational modification enzymes that citrullinate (deiminate) protein arginine residues in a Ca^2+^‐dependent manner. Enzymatic citrullination abolishes positive charges of native protein molecules, inevitably causing significant

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## Abstract Peptidylarginine deiminases (PADs) are Ca2t+-dependant post-translational modification enzymes that catalyze the citrullination of protein arginyl residues. PAD type 2 (PAD2) is thought to be involved in some processes of neurodegeneration and myelination in the central nervous system.