Design, synthesis and biological evaluat
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Ying Yang; Lei Shi; Yang Zhou; Huan-Qiu Li; Zhen-Wei Zhu; Hai-Liang Zhu
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Article
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2010
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Elsevier Science
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English
β 321 KB
Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a crucial role in the process of cancer angiogenesis. A series of quinoline amide derivatives were prepared and found to be good inhibitors of VEGFR-2. The inhibitory activities were investigated against VEGFR-2 kinase and human umbilical