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The design and synthesis of YC-1 analogues as probes for soluble guanylate cyclase

โœ Scribed by Kirk W. Hering; Jennifer D. Artz; William H. Pearson; Michael A. Marletta


Book ID
108073858
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
199 KB
Volume
16
Category
Article
ISSN
0960-894X

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Synergistic activation of soluble guanyl
โœ James R. Stones; Michael A. Marletta ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 880 KB

## Background: Nitric oxide (.no) is used in biology as both an intercellular signaling agent and a cytotoxic agent. in signaling, submicromolar quantities of .no stimulate the soluble isoform of guanylate cyclase (sgc) in the receptor cell. .no increases the vmax of this heterodimeric hemoprotein