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Potentiation of YC-1 activation of soluble guanylate cyclase by NO donors and the increase of the synergistic effect of YC-1 on the NO-dependent activation of the enzyme by 1,2,3-triazolyl-1,2,5-oxadiazole derivatives

โœ Scribed by Severina, I. S.; Pyatakova, N. V.; Shchegolev, A. Yu.; Rozhkov, V. Yu.; Batog, L. V.; Makhova, N. N.


Book ID
125395994
Publisher
Pleiades Publishing
Year
2014
Tongue
English
Weight
161 KB
Volume
8
Category
Article
ISSN
1990-7508

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Synergistic activation of soluble guanyl
โœ James R. Stones; Michael A. Marletta ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 880 KB

## Background: Nitric oxide (.no) is used in biology as both an intercellular signaling agent and a cytotoxic agent. in signaling, submicromolar quantities of .no stimulate the soluble isoform of guanylate cyclase (sgc) in the receptor cell. .no increases the vmax of this heterodimeric hemoprotein