## Abstract For Abstract see ChemInform Abstract in Full Text.
The Design and Preparation of Metabolically Protected New Arylpiperazine 5-HT1A Ligands.
β Scribed by Manish Tandon; Mary-Margaret O'Donnell; Alex Porte; David Vensel; Donglai Yang; Rocio Palma; Alan Beresford; Mark A. Ashwell
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 94 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The synthesis and evaluation as 5-HT 1A and 5-HT 7 serotonin receptor ligands of the two sets of O-substituted hydroxybenzamides, structurally related to 2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]pro-poxy}benzamide (1), (K i 5-HT 1A ΒΌ 21 nM, 5-HT 7 ΒΌ 234 nM) are reported. To affect the affinity for 5-
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