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The dependence of pacemaker discharge of Aplysia neurons upon Na+ and Ca++

✍ Scribed by David Carpenter; Rufus Gunn

Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
477 KB
Volume
75
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

In total absence of Na^+^ some identified neurons of Aplysia, after a period of silence, resume pacemaker discharge in the normal pattern with normal action potentials, while other identified neurons remain silent. In absence of Ca^++^ all pacemaker neurons increase spontaneous discharge and develop abnormal bursting patterns. Those neurons which discharge spontaneously in Na^+^ free solutions show much less dependence on Na^+^ and much greater dependence on Ca^++^ for action potentials initiated by electrical stimulation than do those neurons which do not fire spontaneously in absence of Na^+^. In absence of both Na^+^ and Ca^++^ all neurons become inexcitable, but much more rapidly at higher temperatures.

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