The degree of potentiation is associated with synaptic number during the maintenance of long-term potentiation in the rat dentate gyrus
โ Scribed by Andrew C.W Weeks; Tammy L Ivanco; Janelle C LeBoutillier; Ronald J Racine; Ted L Petit
- Book ID
- 114003983
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 133 KB
- Volume
- 798
- Category
- Article
- ISSN
- 0006-8993
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Changes in synaptic structure have been reported following the induction of long-term potentiation (LTP). The structure of synapses during the intermediate maintenance of LTP has yet to be fully characterized in chronically implanted freely moving animals. The present study examined synapses in the
Long-term potentiation (LTP) in synapses of the medial perforant pathway of the rat dentate gyrus has been studied using the whole-cell voltage clamp technique and a standard hippocampal slice preparation. The rate of LTP induction by 2-4 brief trains of stimuli at 100 Hz, paired with postsynaptic d
Long-term potentiation (LTP), one of the most compelling models of learning and memory, has been associated with changes in synaptic morphology. In this study, LTP was induced and animals were sacrificed 1 h after the stimulation of the LTP group (induction / early maintenance phase). Synapses in th