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The cytotoxic and antifungal activities of two new sesquiterpenes, malfilanol A and B, derived from Malbranchea filamentosa

✍ Scribed by Wakana, Daigo; Hosoe, Tomoo; Wachi, Hiroshi; Itabashi, Takeshi; Fukushima, Kazutaka; Yaguchi, Takeshi; Kawai, Ken-ichi


Book ID
109869100
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
107 KB
Volume
62
Category
Article
ISSN
0021-8820

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Jaspines A and B: two new cytotoxic sphi
✍ VΓ©ronique Ledroit; CΓ©cile Debitus; Catherine Lavaud; Georges Massiot πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m