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The Cytoplasmic Domain of C-CAM1 Tumor Suppressor Is Necessary and Sufficient for Suppressing the Tumorigenicity of Prostate Cancer Cells

✍ Scribed by Vicky T. Estrera; Weiping Luo; Dillon Phan; Karen Earley; Douglas C. Hixson; Sue-Hwa Lin


Book ID
115584539
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
111 KB
Volume
263
Category
Article
ISSN
0006-291X

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## BACKGROUND. Recently, we demonstrated that expression of C-CAM1, an immunoglobulin (Ig)-like cell adhesion molecule (CAM), was diminished in both prostate intraepithelial neoplasia and cancer lesions, indicating that loss of C-CAM1 expression may be involved in the early events of prostate carc