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Suppression of tumorigenicity of breast cancer cells by an epithelial cell adhesion molecule (C-CAM1): the adhesion and growth suppression are mediated by different domains

✍ Scribed by Luo, Weiping; Wood, Christopher G; Earley, Karen; Hung, Mien-Chie; Lin, Sue-Hwa

Book ID: 110060622
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 422 KB
Volume: 14
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1200999

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## Abstract A key step in human colon cancer development includes the hyperactivation of Wnt/β‐catenin signaling and the induction of β‐catenin‐TCF target genes that participate in colon cancer progression. Recent studies identified members of the immunoglobulin‐like cell adhesion molecules (IgCAM)