## Abstract EpsteinβBarr virus (EBV) is implicated in the pathogenesis of several lymphoid and epithelial neoplasms. Latent membrane protein 1 (LMP1) is the major viral oncogene and it is controversial whether tumor LMP1 variants reflect their geographical predominance or are associated with enhanc
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The cytoplasmic amino-terminus of the Latent Membrane Protein-1 of Epstein-Barr Virus: relationship between transmembrane orientation and effector functions of the carboxy-terminus and transmembrane domain
β Scribed by Coffin III, William F; Erickson, Kimberly D; Hoedt-Miller, Marloes; Martin, Jennifer M
- Book ID
- 110065937
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 565 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0950-9232
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The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletio