We reported previously that a characteristic Epstein-Barr virus latent membrane protein 1 (EBV-LMP1) gene was associated with nasopharyngeal carcinoma (NPC) in Hong Kong. It showed a 30 bp deletion at the carboxyl terminus with specific amino acid substitution Asp at codon 335 with reference to Gly
β¦ LIBER β¦
Nucleotide Sequences and Functions of the Epstein-Barr Virus Latent Membrane Protein 1 Genes Isolated from Salivary Gland Lymphoepithelial Carcinomas
β Scribed by Kai Yu Jen; Masaya Higuchi; Jun Cheng; Jiang Li; Lan Yan Wu; Ying Fang Li; Han Liang Lin; Zhilong Chen; Vladimir Gurtsevitch; Masahiro Fujii; Takashi Saku
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 527 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0920-8569
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Two genes encoding the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) were isolated from a single case of Hodgkin's disease (HD) and were tested for their biological activities. The LMP1 gene from the Reed-Sternberg cells contained point mutations relative to the prototype LMP1 gen