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Difference of Epstein–Barr virus isolates from Japanese patients and African Burkitt’s lymphoma cell lines based on the sequence of latent membrane protein 1

✍ Scribed by Kyosuke Kanai; Yukio Satoh; Yuriko Saiki; Haruo Ohtani; Takeshi Sairenji


Publisher
Springer
Year
2007
Tongue
English
Weight
284 KB
Volume
34
Category
Article
ISSN
0920-8569

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Two genes encoding the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) were isolated from a single case of Hodgkin's disease (HD) and were tested for their biological activities. The LMP1 gene from the Reed-Sternberg cells contained point mutations relative to the prototype LMP1 gen