The genotoxicity of rifampicin was tested for sister chromatic exchange in bone marrow cells and for structural chromosomal aberrations in mouse germ cells. Sister chromatid exchange frequency increased after 160, 240 and 310 mg kg-' body wt. doses but not after 80 mg kg-'. In spermatocytes, 80 mg
The cytogenetic and hepatotoxic effects of dioxin on mouse liver cells
β Scribed by Antone L. Brooks; Scott W. Jordan; Kallol K. Bose; Jennifer Smith; David C. Allison
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 683 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0742-2091
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The present study was undertaken to assess, __in vitro__, the hepatotoxic potential of the foodβborne mycotoxin, deoxynivalenol (DON), using rat (Clone9 and MH1C1), mouse (NBL CL2) and human (WRL68 and HepG2) liver cells in culture. The cells were treated with DON for 24βh at 37 Β°C in 5
Diflubenzuron (DFB), a potent inhibitor of insect chitin synthesis, was administered to Swiss Webster mice in a 30-day oral intubation study. Animal groups received either no treatment, vehicle control (Polyethylene glycol 400), or DFB suspensions at doses of 125, 500, and 2,000 mg/kg body weight. H