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The critical period of valproate exposure to induce autistic symptoms in Sprague–Dawley rats

✍ Scribed by Ki Chan Kim; Pitna Kim; Hyo Sang Go; Chang Soon Choi; Sung-Il Yang; Jae Hoon Cheong; Chan Young Shin; Kwang Ho Ko

Book ID
116923741
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
650 KB
Volume
201
Category
Article
ISSN
0378-4274

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## Abstract The critical period for increased neonatal mortality induced by perfluorooctane sulfonate (PFOS) exposure was evaluated in the rat. Timed‐pregnant Sprague‐Dawley rats were treated by oral gavage with 25 mg/kg/d PFOS/K^+^ on four consecutive days (gestation days (GD) 2–5, 6–9, 10–13, 14–