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Influence of perinatal genistein exposure on the development of MNU-induced mammary carcinoma in female Sprague–Dawley rats

✍ Scribed by Jihong Yang; Hiroyuki Nakagawa; Koji Tsuta; Airo Tsubura


Book ID
117469711
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
237 KB
Volume
149
Category
Article
ISSN
0304-3835

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## Abstract The effect of oral administration of diazoxide on rats bearing mammary carcinomas induced by dimethylbenzanthracene (7,12‐DMBA) or methylnitro sourea (MNU) was investigated. Administration of 300 mg/kg diazoxide caused mild reversible diabetes with maximum glucose levels of 305 ± 74 (co