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The covalent interaction of 1,4-dibromobenzene with rat and mouse nucleic acids: in vivo and in vitro studies

✍ Scribed by Colacci, Annamaria; Bartoli, Silvana; Bonora, Bruna; Mazzullo, Mario; Niero, Alessandra; Perocco, Paolo; Silingardi, Paola; Grilli, Sandro


Book ID
121885140
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
445 KB
Volume
54
Category
Article
ISSN
0378-4274

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## Abstract ^14^C‐labelled carbon tetrachloride binds __in vivo__ to DNA of mouse liver and to ^r^RNA of rat liver if the animals have been pretreated with 3‐methylcholanthrene. A noticeable amount of radioactivity is also observed in liver proteins. In vitro carbon tetrachloride is activated by mi