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The Cost-Effectiveness of Drug Regulation: The Example of Thorough QT/QTc Studies

✍ Scribed by Bouvy, J C; Koopmanschap, M A; Shah, R R; Schellekens, H

Book ID
121400440
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
215 KB
Volume
91
Category
Article
ISSN
0009-9236

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## Introduction Dapagliflozin is a first-in-class sodium-glucose transporter 2 (SGLT2) inhibitor under investigation for the treatment of type 2 diabetes mellitus. A thorough QTc study was conducted, according to International Conference on Harmonization E14 guidelines, to characterize the effect o