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The core protein of HCV genotype 3A, 3H and 1B induces lipid accumulation in a hepatoma cell line

✍ Scribed by K. Abid; C. Rossi; P. Latorre; L. Rubbia-Brandt; F. Negro

Book ID
117372570
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
161 KB
Volume
38
Category
Article
ISSN
0168-8278

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Both molecular and clinical evidence support a link between HCV infection and insulin resistance. We examined the in vitro interaction between the HCV core protein of genotypes 3a and 1b with the insulin-signaling pathway. We measured the expression levels of insulin receptor substrate 1 (IRS-1), IR