The coordinated action of protein tyrosine phosphatases and kinases in cell signaling
โ Scribed by Hong Sun; Nicholas K. Tonks
- Book ID
- 113408670
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 647 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0968-0004
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Intracellular signaling proteins are very often regulated by site-specific phosphorylation. For example, growth factor receptors in eukaryotic cells contain intrinsic tyrosine kinase activity and use inter- and intra-molecular interactions to recruit and orient potential protein substrates for phosp
Protein-tyrosine phosphatases (PTPases) play an important role in the regulation of insulin action by dephosphorylating the active (autophosphorylated) form of the insulin receptor and attenuating its tyrosine kinase activity. PTPases can also modulate post-receptor signalling by catalyzing the deph